基本信息
张友玉,博士,二级教授,博士生导师。主要从事化学生物学及纳米分析化学等领域的研究。主持国家自然科学基金面上项目5项,国家基金重点项目协作项目1项,省部级重点及一般项目10余项。以第一作者和通讯作者在Sci. Adv.,Angew. Chem. Int. Ed., Anal. Chem., Chem. Commun.等国际著名刊物上发表高水平研究论文200余篇,获国家授权发明专利7项。获湖南省自然科学奖二等奖1项,湖南省科学技术进步奖二等奖1项,中国分析测试学会科学技术奖(CAIA奖)二等奖1项。获2018年奥门银河误乐城芙蓉百岗明星称号。
主持课题(部分)
1.国家自然科学基金(21874042),癌细胞外泌体的生物分析新方法与临床样品检测研究。在研。
2.国家自然科学基金(21475043),Ⅳ族元素量子点的电化学制备及其在生物分析中的应用。
3.国家自然科学基金(21275051),基于上转换纳米编码探针的多种肿瘤标志物同时检测技术。
4.国家自然科学基金(20975037),基于功能化蛋白核壳纳米编码信标的核酸适体阵列传感技术研究。
5.国家自然科学基金(20675030),基于纳米颗粒编码的DNA单碱基突变检测技术研究。
6.国家自然科学基金协作项目(21327806),生物荧光探针的合成与表征。
代表性论文(部分)
1.Dan Liu,Kangkang Weng,Shaoyong Lu,Fu Li,Hannikezi Abudukeremu,Lipeng Zhang,Yuchen Yang,Junyang Hou,Hengwei Qiu,Zhong Fu,Xiyu Luo,Lian Duan,Youyu Zhang*,Hao Zhang*,Jinghong Li,Direct optical patterning of perovskite nanocrystals with ligand cross-linkers.Science Advances,2022 8,(11),eabm8433.
2.Feng Chen,Qiujun Lu,Linna Huang,Biwu Liu,Meiling Liu,Youyu Zhang*,Juewen Liu*,DNA Triplex and Quadruplex Assembled Nanosensorsfor Correlating K+and pH in Lysosomes.Angewandte Chemie International Edition,2021 60,5453-5458.
3.Jianhui Deng,Qiujun Lu,Yuxin Hou,Meiling Liu*,Haitao Li,Youyu Zhang*,Shouzhuo Yao,Nanosensor Composed of Nitrogen-Doped Carbon Dots and Gold Nanoparticles for Highly Selective Detection of Cysteine with Multiple Signals.Analytical Chemistry,2015 87,(4),2195-2203.
4.Xiaojiao Chen,Yangzhong Wang,Youyu Zhang*,Zhuhai Chen,Yang Liu*,Zhaolong Li,Jinghong Li,Sensitive Electrochemical Aptamer Biosensor for Dynamic Cell Surface N-Glycan Evaluation Featuring Multivalent Recognition and Signal Amplification on a Dendrimer-Graphene Electrode Interface.Analytical Chemistry,2014 86,(9),4278-4286.
5.Yinhui Yi,Gangbing Zhu,Chang Liu,Yan Huang,Youyu Zhang*,Haitao Li,Jiangna Zhao,Shouzhuo Yao,A Label-Free Silicon Quantum Dots-Based Photoluminescence Sensor for Ultrasensitive Detection of Pesticides.Analytical Chemistry,2013 85,(23),11464-11470.
6.Youyu Zhang,Zhiwen Tang,Jun Wang,Hong Wu,Aihui Maham,Yuehe Lin*,Hairpin DNA Switch for Ultrasensitive Spectrophotometric Detection of DNA Hybridization Based on Gold Nanoparticles and Enzyme Signal Amplification.Analytical Chemistry,2010 82,(15),6440-6446.
7.Qiujun Lu,Jianhui Deng,Yuxin Hou,Haiyan Wang,Haitao Li,Youyu Zhang*,One-step electrochemical synthesis of ultrathin graphitic carbon nitride nanosheets and their application to the detection of uric acid.Chemical Communications,2015 51,(61),12251-12253.
8.Qiujun Lu,Jianhui Deng,Yuxin Hou,Haiyan Wang,Haitao Li,Youyu Zhang*,Shouzhuo Yao,Hydroxyl-rich C-dots synthesized by a one-pot method and their application in the preparation of noble metal nanoparticles.Chemical Communications,2015 51,(33),7164-7167.
9.Qiong Chen,Meiling Liu,Jiangna Zhao,Xue Peng,Xiaojiao Chen,Naxiu Mi,Bangda Yin,Haitao Li,Youyu Zhang*,Shouzhuo Yao,Water-dispersible silicon dots as a peroxidase mimetic for the highly-sensitive colorimetric detection of glucose.Chemical Communications,2014 50,(51),6771-6774.
10.Mingjie Wei,Peng Yin,Youming Shen,Lingli Zhang,Jianhui Deng,Shanyan Xue,Haitao Li,Bin Guo,Youyu Zhang*,Shouzhuo Yao,A new turn-on fluorescent probe for selective detection of glutathione and cysteine in living cells.Chemical Communications,2013 49,(41),4640-4642.
11.Yinhui Yi,Jianhui Deng,Youyu Zhang*,Haitao Li,Shouzhuo Yao,Label-free Si quantum dots as photoluminescence probes for glucose detection.Chemical Communications,2013 49,(6),612-614.
12.Jianhui Deng,Qiujun Lu,Naxiu Mi,Haitao Li,Meiling Liu,Mancai Xu,Liang Tan,Qingji Xie,Youyu Zhang*,Shouzhuo Yao,Electrochemical Synthesis of Carbon Nanodots Directly from Alcohols.Chemistry-a European Journal,2014 20,(17),4993-4999.
13.Youyu Zhang,Zhiwen Tang,Jun Wang,Hong Wu,Chiann-Tso Lin,Yuehe Lin*,Apoferritin nanoparticle: a novel and biocompatible carrier for enzyme immobilization with enhanced activity and stability.Journal Of Materials Chemistry,2011 21,(43),17468-17475.
14.Zile Zhou,Shengyou Chen,Yinghui Huang,Biao Gu,Jiaqi Li,Cuiyan Wu,Peng Yin,Youyu Zhang*,Haitao Li*,Simultaneous visualization and quantification of copper (II) ions in Alzheimer's disease by a near-infrared fluorescence probe.Biosensors & Bioelectronics,2022 198,113858.
15.Mingxia Li,Haiyan Wang,Xiaoxia Wang,Qiujun Lu,Haitao Li,Youyu Zhang*,Shouzhuo Yao,Ti3C2/Cu2O heterostructure based signal-off photoelectrochemical sensor for high sensitivity detection of glucose.Biosensors & Bioelectronics,2019 142.
16.Qiujun Lu,Haiyan Wang,Yalan Liu,Yuxin Hou,Haitao Li,Youyu Zhang*,Graphitic carbon nitride nanodots: As reductant for the synthesis of silver nanoparticles and its biothiols biosensing application.Biosensors & Bioelectronics,2017 89411-416.
17.Aijin Fang,Hongyu Chen,Haitao Li,Meiling Liu*,Youyu Zhang*,Shouzhuo Yao,Glutathione regulation-based dual-functional upconversion sensing-platform for acetylcholinesterase activity and cadmium ions.Biosensors & Bioelectronics,2017 87545-551.
18.Aijin Fang,Qiongqiong Wu,Qiujun Lu,Hongyu Chen,Haitao Li,Meiling Liu*,Youyu Zhang*,Shouzhuo Yao,Upconversion ratiometric fluorescence and colorimetric dual-readout assay for uric acid.Biosensors & Bioelectronics,2016 86664-670.
19.Qian Long,Aijin Fang,Yanqing Wen,Haitao Li,Youyu Zhang*,Shouzhuo Yao,Rapid and highly-sensitive uric acid sensing based on enzymatic catalysis-induced upconversion inner filter effect.Biosensors & Bioelectronics,2016 86109-114.
20.Qiongqiong Wu,Aijin Fang,Haitao Li,Youyu Zhang*,Shouzhuo Yao,Enzymatic-induced upconversion photoinduced electron transfer for sensing tyrosine in human serum.Biosensors & Bioelectronics,2016 77957-962.
21.Qian Long,Haitao Li,Youyu Zhang*,Shouzhuo Yao,Upconversion nanoparticle-based fluorescence resonance energy transfer assay for organophosphorus pesticides.Biosensors & Bioelectronics,2015 68168-174.
22.Meiling Liu,Jianhui Deng,Qiong Chen,Yan Huang,Linping Wang,Yan Zhao,Youyu Zhang*,Haitao Li,Shouzhuo Yao*,Sensitive detection of rutin with novel ferrocene benzyne derivative modified electrodes.Biosensors & Bioelectronics,2013 41275-281.
23.Jie Zhao,Youyu Zhang*,Haitao Li,Yanqing Wen,Xiaoyu Fan,Fanbo Lin,Liang Tan,Shouzhuo Yao,Ultrasensitive electrochemical aptasensor for thrombin based on the amplification of aptamer-AuNPs-HRP conjugates.Biosensors & Bioelectronics,2011 26,(5),2297-2303.
24.Min Ye,Youyu Zhang*,Haitao Li,Yuqin Zhang,Ping Tan,Hao Tang,Shouzhuo Yao,A novel method for the detection of point mutation in DNA using single-base-coded CdS nanoprobes.Biosensors & Bioelectronics,2009 24,(8),2339-2345.
25.Mingxia Li,Qiujun Lu,Meiling Liu,Peng Yin,Cuiyan Wu,Haitao Li,Youyu Zhang*,Shouzhuo Yao,Photoinduced Charge Separation via the Double-Electron Transfer Mechanism in Nitrogen Vacancies g-C3N5/BiOBr for the Photoelectrochemical Nitrogen Reduction.Acs Applied Materials & Interfaces,2020 12,(34),38266-38274.
26.Dan Liu,Gong Zhang,Qinghua Ji,Youyu Zhang*,Jinghong Li*,Synergistic Electrocatalytic Nitrogen Reduction Enabled by Confinement of Nanosized Au Particles onto a Two-Dimensional Ti3C2Substrate.Acs Applied Materials & Interfaces,2019 11,(29),25758-25765.
27.Na Huang,Si Zhang,Liuqing Yang,Meiling Liu*,Haitao Li,Youyu Zhang*,Shouzhuo Yao,Multifunctional Electrochemical Platforms Based on the Michael Addition/Schiff Base Reaction of Polydopamine Modified Reduced Graphene Oxide: Construction and Application.Acs Applied Materials & Interfaces,2015 7,(32),17935-17946.
28.Qiongqiong Wu,Hongyu Chen,Aijin Fang,Xinyang Wu,Meiling Liu*,Haitao Li,Youyu Zhang*,Shouzhuo Yao,Universal Multifunctional Nanoplatform Based on Target-Induced in Situ Promoting Au Seeds Growth to Quench Fluorescence of Upconversion Nanoparticles.Acs Sensors,2017 2,(12),1805-1813.
29.Qujun Lu,Hu Dong,Jiali Hu,Linna Huang,Youyu Zhang*,Mingxia Li,Meiling Liu,Yaqian Li,Cuiyan Wu*,Haitao Li,Insight into the Effect of Ligands on the Optical Properties of Germanium Quantum Dots and Their Applications in Persistent Cell Imaging.Langmuir,2020 36,(41),12375-12382.
30.Jiali Hu,Qiujun Lu,Cuiyan Wu,Meiling Liu,Haitao Li,Youyu Zhang*,Shouzhuo Yao,Synthesis of Fluorescent and Water-Dispersed Germanium Nanoparticles and Their Cellular Imaging Applications.Langmuir,2018 34,(30),8932-8938.
联系方式
Email:zhangyy@hunnu.edu.cn,zhangyy0101@126.com
Tel:+86-13787296080
(更新于2022年3月)